Manchester United came back from a goal down to beat Brighton 2-1 thanks to second-half goals from Marcos Rashford and Mason Greenwood.
Former Manchester United striker Danny Welbeck put Brighton in front from close range after 13 minutes, but Rashford equalized in the 62nd minute after a pass from Bruno Fernandes on Sunday, Xinhua news reports.
Mason Greenwood won the game in the 82nd minute after he stooped to nod home Paul Pogba's mishit shot at the far post.
Chelsea was affected by the international break and also by a 29th-minute red card for defender Thiago Silva, who was sent off just two minutes after Christian Pulisic had put his side in front against West Brom, who travelled to Stamford Bridge with just 20 league goals all season.
The rest of the game was a reminder that football still has the capacity to produce surprises as Matheus Pereira turned the score around in first-half injury time.
Further goals from Callum Robinson and Mbaye Diagne in the second half made it 4-1 for West Brom and although Mason Mount pulled a goal back for Chelsea there was still time for Robinson to add a fifth for West Brom in injury time.
Diogo Jota scored twice as Liverpool warmed up for next week's Champions League clash against Real Madrid with a 3-0 win away to Arsenal. Joe Wilcock's 85th-minute goal earned Newcastle a vital point at home to Tottenham in a game that had plenty of alternatives.
A rare Joelinton goal gave Newcastle a deserved lead after 28 minutes only for two goals from Harry Kane after 30 and 34 minutes to leave Newcastle looking groggy. Kane hit the outside of the post in the closing minutes and that was a big let-off for Steve Bruce's strugglers as Wlicock's goal went in off the underside of the bar two minutes later.